Malignant Mixed Mullerian Tumor: An Immunohistochemical Study

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Malignant Mixed Mullerian Tumor: An Immunohistochemical Study

Malignant mixed Mullerian tumor (MMMT) is an uncommon aggressive neoplasm composed of both malignant epithelial and mesenchymal components. In this study, immunohistochemical stains of germ cell markers, including SALL4, OCT3/4, glypican-3, and alpha-fetal protein (AFP), and CDX2 were performed in a series of MMMTs. SALL4 nuclear immunoreactivity was detected in 6 out of 19 cases (33%). The sta...

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Malignant Mixed Mullerian Tumor of Cervix

Malignant mixed Mullerian tumors of the cervix are very rare tumors, constituting only 0.005% of all cervical malignancies. It usually presents with abnormal vaginal bleeding in post-menopausal women. The tumor has high rates of metastasis, so careful management including surgery, chemotherapy and/or radiotherapy is done for these patients. Here, we present a case of a 47 year old woman who pre...

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Serous Ovarian Carcinoma Recurring as Malignant Mixed Mullerian Tumor

Only five cases of recurrence of malignant mixed Mullerian tumor (carcinosarcoma) from the ovarian carcinoma have been published in the literature to our knowledge. A 64-year-old woman first underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy because of pelvic mass. Histological diagnosis was serous papillary carcinoma of the left ovary. After six courses of chemotherap...

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Uterine Malignant Mixed Mullerian Tumor: Review of Recent Literature

Uterine Malignant Mixed Mullerian Tumor (MMMT) is an uncommon neoplasm with aggressive clinical course. It shares similar etiology, clinical and pathologic features of high-grade endometrial carcinoma. As such, uterine MMMT has been recently regarded as high grade de-differentiated endometrial carcinoma. Histologically, uterine MMMT is composed of an admixture of malignant epithelial and mesenc...

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Malignant mixed Mullerian tumour of the uterus

BACKGROUND A malignant mixed Mullerian tumour (MMMT) of the uterine corpus is an extremely rare and aggressive malignancy. There are very few studies regarding the outcome of MMMT patients in India. Hence, we conducted the present study to analyse the outcome of MMMTs at our institute. OBJECTIVE To study the clinical profile, prognostic features, and treatment outcome of MMMT with multimodal ...

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ژورنال

عنوان ژورنال: Pathology Research International

سال: 2012

ISSN: 2090-8091,2042-003X

DOI: 10.1155/2012/569609